Simply Horses Farrier In Need Of Help

One of the Farriers we work along side with here at Simply Horses contacted us and requested our assistance with one of his projects.

Being really intrigued in his career by horses with “odd” feet he decided to go scientific about it…;-) (when in reality he is studing towards a degree) , and do some measurements of pedal bone, different widths and angles of some of his clients’ horses’ feet with this problem.

So… for last 5 weeks, every wednesday we go with our farrier friend and use our X-ray equipment and our horse sedation skills in the name of the science.

What we do: sedate horses and take Xrays of both front feet (lateral and antero-palmar views) and submit them for assesment and measurements.

Then our farrier makes his measurements of horse’s foot: angles, widths and lenghts to find a conection between all of these “numbers”.

At the moment we are in the gathering-data phase of the study.

Next will be the analyzing phase and hopefully we will update you, our friends when result will come through.

We wish our farrier best of luck in his study and with his dissertation and we’ll be interested in his findings.

… and, if you got a horse with “odd” feet , you never know … you might hear from us…

Vio Doran MRCVS

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Winter and Mud Fever has arrived at Simply Horses Vets! Horse owners beware.

Winter is defiantly here the rain and for some of us the snow has started to set in. If your horse is exposed to prolonged wet weather then the skin on your horses legs will soften resulting in a higher susceptibility to mud fever. This should make you as a horse owner take particular care of your horses legs, checking them thoroughly on a regular basis to ensure that mud fever has not started to set in. Remember prevention is better than cure and the quicker you act the better for your horse.

Keep your horses legs looking the way they should, as they say No leg no horse ….

by Tatinauk under CC BY-ND  with wpseopix.com

 

 

Mud Fever Simply Horses
by eXtensionHorses under CC BY-SA  with wpseopix.com

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Movement

Movement

Dr Bowker conducted a study to compare the movement of the pastured horse compared to the stabled horse.

On average the pastured horses took 8,000-10,000 steps per day.

The stabled horses averaged 800!

Whilst conducting the study he noticed that pastured horses tended to sleep mostly in the early hours of the morning. So he wondered if it would make much difference if the horses were just stabled at night, as this would include the sleep hours.

Interestingly the horses that were stabled at night didn’t move much more than the 24/7 stabled horses when they were turned out during the day.

He theorized that the act of stabling shuts down the horse’s innate movement characteristic.

Interesting!

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What is Mud fever & how to deal with it

Mud Fever
The time of year is certainly here where mud fever can become a concern for horse owners. Mud Fever occurs during the wet winter months and is principally caused by the bacterium Dermatophilus congolensis. It occurs because we expose our horses to muddy environments that winter months bring. Mud fever is essentially a form of dermatitis which can affect the skin anywhere on the lower limbs, the back and quarters.
All horses can be affected and these areas can be painful swollen and even cause lameness. If horses become severely affected without treatment they can become very painful, lethargic, depressed and have a loss of appetite. Therefore it is very important to prevent mud fever or catch early signs of it. Below are some helpful tips.

Signs of mud fever
Crusty scabs
Small, circular, slightly ulcerated, moist lesions beneath scabs
Yellowish discharge between the skin and overlying scab
The scabs typically have a concave underside with the hair roots protruding
Eventual hair loss leaving raw-looking, inflamed skin underneath
Heat, swelling and pain on pressure on the limb

Preventing mud fever
Ensure bedding is clean, dry and has a good cover on the concrete
Keep horses prone to mud fever out of the rain and mud as much as realistically possible
Avoid over-washing and unnecessary wetting of the skin
Make sure the skin is dry as much as possible. Dry wet skin with a soft towel 
Clip away any excess feathering but try to aviod clipping the legs out
If bandaging, ensure limbs are clean and dry first
Periodically disinfect all equipment, gear and stable surfaces, as they could harbour dermatophilus spores
Rotate paddocks to avoid poaching. In particular keep an eye on gateways as horses tend to stand in them and they are usually the wettest part of the field
Remove any scabs carefully without constantly picking at them. Remove with a wash such as Hibiscrub

Treatment of mud fever
There are many treatments for mud fever. But it has to be remembered that with any condition for which there are a large number of possible treatments, it is often because nothing is a guaranteed success. Keeping the skin clean and dry is the basis of preventing and treating the condition. 

Environment
The first step is to remove the horse from the cause, eg: the wet and the mud. Stabling undoubtedly helps the situation, however, if the horse is kept in all the time and not exercised, the legs will tend to swell.
If the horse is able to walk out in dry conditions this will always help the process because the blood will then circulate better which will improve the rate of healing. 
The horse should be stabled with a clean, dry bed. Dirty bedding will increase the risk of infection.

Scabs
More specific treatment has to penetrate the causal organisms under the scabs, so these must be lifted when ready. Soaking the crusts or scabs in warm soapy water  will soften them and make the procedure much less painful for the horse. When the crusts and scabs have been removed the affected skin should be treated with an anti-bacterial solution , such as Hibiscrub, and then left for 5 to 10 minutes. The treated area should then be rinsed then dried with a dry clean towel.

Bandaging
Bandaging an affected limb can be a good way of keeping it clean and dry, but only if the skin has been properly dealt with beforehand, and the correct bandaging technique is used. Bandaging that’s too tight or has moisture trapped underneath can allow an infection to flare up again.
In the early stages, open wounds resulting from the removal of the scabs should be covered with a non-stick dressing applied under cotton wool or gamgee, held in place with bandages. This keeps the lower limb warm, clean and dry; it may help to leave the legs unbandaged for at least an hour a day to allow the area to ‘breathe’.

Creams and treatments
There are numerous topical treatments that can be used as an emollient to maintain hydration of the skin. These include soothing ointments, gels and creams, some of which contain antibiotics. Recent additions to the mudfever range are a dressing impregnated with silver which has been shown to have strong antibacterial properties. Early trials with these products look promising. Your vet will recommend the most suitable for your horse.

Antibiotics
Severe cases with obvious infection often need a long course of antibiotics. These may need to be continued for 7–10 days after the soreness has settled down. Your vet may also prescribe non-steroidal anti-inflammatory drugs such as phenylbutazone to reduce the pain and swelling.

Mud fever is a difficult condition to treat and it may take many weeks for the lesions to heal completely. If the case is straightforward and the causes are treated or removed, then the disease will usually resolve quickly. While most cases can be resolved, some chronic epidermal scarring and weakening may be left, contributing to a tendency to re-infection. Management changes to help prevent any further problems are worth pursuing. In problem cases your vet might take a blood sample, to check liver function if the dermatitis is limited to white areas of skin only. Be vigilant. The sooner you spot the first tell tale signs of mud fever, the quicker you can take action and so prevent a lengthy, and costly, recovery.
If your horse or pony has a severe case of mud fever – i.e. He has very swollen legs or is lame you should seek advice from your veterinary surgeon who may prescribe Antibiotics.

 

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Durham county B.H.S meeting

The BHS Annual Meeting saw the election of a new Chairman, Carole Swinburn and some new committee members to help with our work; we also said goodbye to our previous Chairman, Kate Rogers, who is relocating to London and our Treasurer for the last 24 years, Judy Hare.
One of the key roles of the BHS is to educate the membership and equestrians in general so the business part of the meeting was followed by a talk from Paul Proctor on the most recent best practice in avoiding and managing Laminitis, ECD and insulin resistance in horses and ponies. This dreadful condition seems to be affecting more equines than in the past and responsible horse owners are keen to be equipped with the latest ammunition to protect their animals.
 
The committee tries to respond to the membership and offer them talks and events they have requested. During the previous year this has included dressage competitions, cross country schooling, clear round show jumping and summer veterinary talks. These events were generally well supported  and brought in revenue to fund the rest of our work.
 
All of the committee are volunteers who give their time in the interest of the horse. Welfare is a key strand in the work of the BHS Durham Committee. Our main officer, Christine Allison is based in the south of the county, along with two of her assistants, Delyth and Julie. We have two new welfare assistants, Emma and Penny, in the north of the county. They check on every case reported to them, sometimes attending three cases a day during the winter, giving advice and practical assistance to horse owners/keepers. This is all part of the educative role of the BHS and training is given to officers before they are allowed to do this work. In severe cases of cruelty or when enforcement is necessary, the team work with the police and RSPCA.
 
Another essential role is in Road Safety. Kay Redfearn is a qualified trainer who works very hard running courses for prospective BHS riding instructors who must have a riding and road safety qualification, as well for pony club groups, riding schools and other riders in the area. The full course and test is for people over the age of twelve years and successful candidates gain an EQL qualification equivalent to a GCSE. Kay also gives talks to livery yards and groups of all ages. One key bit of advice is that of wearing reflective clothing at all times. The minimum recommendation is a tabard for riders and four leg bands for the horse. This can afford a three seconds safety margin for drivers to slow down and avoid accidents. Reflective equipment also allows helicopters and low flying aircraft to take evasive action when encountering horses riders; it also assists rescue services in locating riders when there has been an accident.
 
The access team, currently Marilyn Gibson assisted by Kathy Atkinson, Angela Johnson and Joanne Forster, works with Durham County Council officers to ensure the maintenance and improvement of the Rights of Way network available to horse riders. Nationally, riders have access to just 22% of the ROW network at present but there is a move from DEFRA Minister, Richard Benyon, to encourage local authorities to maximise the use of the ROW network by allowing equestrians to access any suitable tracks available to them. In the meantime we inspect tracks where we have received reports of obstructions, difficult gates and stiles or badly eroded surfaces and we negotiate their repair. We are consulted about proposed developments that might have an affect on routes used by horse riders; theses are often surface mines, quarries and wind farms but sometimes involve private developments and track diversions. We are consulted on new routes that are being developed and we are lucky that in County Durham there is an inclusive attitude that gives equestrian access wherever it can be negotiated with landowners.

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Equine Cushings and metabolic syndrome

Equine Cushing’s Disease & Metabolic Syndrome
Does your Pony seem to gain weight on air alone? Or do they keep getting bouts of laminitis even when you’ve tried so hard to prevent it? Your pony may be suffering from Cushing’s Disease and/or Equine Metabolic Syndrome.  This fact sheet will hopefully help you understand these common but often confusing conditions.
EQUINE CUSHING’S DISEASE
What is Equine Cushing’s Disease?
Equine Cushing’s Disease is a dysfunction of part of the endocrine system (organs that are involved in the release of hormones) called the Pituitary gland. The pituitary gland is located at the base of the brain. A specific area of the pituitary gland is affected called the Pars Intermedia and hence another name for this disease is Pituitary Pars Intermedia Dysfunction or PPID. Enlargement of this region of the gland results in increased levels of hormones being released. One of these hormones is called Adrenocorticotropin hormone or ACTH. ACTH travels through the horses bloodstream to the adrenal glands (near the kidneys) and causes the release of Cortisol. Cortisol is a type of steroid, over production of this can explain many of the clinical signs seen with this condition.
Cushings Disease most commonly affects pony breeds however older horses (usually over 15) may also be affected.
What does Equine Cushing’s look like?
Abnormal hair coat and recurrent unexplained bouts of laminitis are the most common clinical signs. The abnormal hair coat can vary from delayed shedding of the winter coat to thick wavy hair growth (upto 10cm) characteristic of this disease, this is called ‘hirsutism’. This occurs as the large pituitary gland impinges on the part of the brain that controls body temperature.
 Other less common signs are increased drinking and urination, lethargy, pot belly and possibly recurrent skin/respiratory infections, increased suseptability to worms and dental disease. You may also notice abnormal deposition of fat, above the horses eye for example where the depression would normally be. You may also notice wasting of the horses skeletal muscles.

Unfortunately the link between Laminitis and Equine Cushing’s Disease is not yet fully understood, it is thought that Cortisol and other similar hormones play a major role in the development of Laminitis, as might a metabolic state called Insulin Resistance.
How is Cushing’s Disease Diagnosed?
Presentation alone may be enough in some cases to make a diagnosis, however in more subtle cases tests to measure ACTH, blood glucose and other hormones may be used.

Treatment & Management of Equine Cushing’s Disease
Currently there is no cure for Equine Cushing’s Disease, thankfully there are a couple of drugs that can help to reduce the effects of the disease and aid management of the affected horse.
Pergolide is probably the most commonly used medication, this comes as a tablet licensed for use in horses called Prascend. Pergolide has been reported to be 80% successful in reducing the severity of Equine Cushing’s Disease.
Trilostane is another drug used for treatment however this does not act directly on the pituitary gland and therefore is not often used anymore.
Management is just as important as medicating affected horses and you should regularly check for wounds and evidence of infection, ensuring prompt veterinary attention where required. Regulary visits from the farrier, dental checks,  routine vaccinations and worm egg counts are also important in ensuring an affect horses health. Simple things like clipping excess hair will go a long way to making a horse more comfortable.

EQUINE METABOLIC SYNDROME
What is Equine Metabolic Syndrome?
Equine Metabolic Syndrome (EMS) is a term vets use to describe horses presenting with obesity and/or large regional fat deposits, insulin resistance and recurrent laminitis.
EMS usually affects young to middle aged horses and native pony type breeds.
A horse with EMS is usually a ‘good doer’ they seem to gain weight on little food intake. Regional fat deposits are commonly seen in the crest of the neck, around the base of the tail and in and around the mammary glands of mares or the sheath of geldings. Fat deposits are not restricted to these areas and may also be seen over the shoulders.
As with Cushing’s Disease the association with EMS anf Laminitis is still not fully understood. It is believed that there is a link between Insulin Resistance and the predisposition for laminitis to occur.
What is Insulin Resistance?
Insulin is a hormone that is produced to regulate the uptake of glucose from the bloodstream following eating allowing it to be stored in cells as an energy source. With Insulin resistance this mechanism does not function properly and the body increases the level of Insulin to attempt to overcome its own insensitivity to Insulin.  An elevated Insulin level therefore can be reflective of Insulin resistance occurring.
Excessive calorific intake resulting in obesity is the primary cause of Insulin Resistance in the horses as in people. It is now known that fat not only acts as an energy store but released hormones and inflammatory mediators that decrease the bodys sensitivity to Insulin.
Why are Ponies Suseptable to EMS?
Native breed ponies have evolved to survive in the UK climate, enduring long periods through the winter when the grass growth is very slow if at all. Fat deposits laid down from eating the lush grass through the spring and summer help the ponies survive these challenging times through the winter, as the pony draws on their reserves to provide the calories they require.
Ponies in the UK now have access to much improved pastures to graze on, they are also provided with extra feeding all year round, often in the form of concentrates and haylage!
How do we diagnose EMS?
As with Cushing’s Disease, in some cases history and presentation alone can be stringly suggestive of EMS, however clinical signs can be confused with Cushing’s Disease and therefore it is important to rule out this disease.  Currently there is no one definitive test for EMS, however blood tests to show levels of Glucose and Insulin and the ratio they have to each other are very uiseful in the diagnosis of EMS.
Treatment and Management of EMS
Weight Loss – buy a weigh tape!
Exercise
Management of both of these require a lot of commitment, discipline and perseverance on the owner’s part! Obese horses should be placed on diet consisting of HAY & VITAMIN/MINERAL supplements ONLY with NO access to pasture. The hay will ideally be mature grassy hay with high stem to leaf ratio.
Legume hay such as alfalfa should be avoided as these contain higher energy contents, if these are the only hay available it should be SOAKED for at least 30 minutes ideally 24hours before presenting to the horse (do not let the horse drink the water the hay has been soaked in, as this defeats the whole object of soaking the hay!) If in doubt…it is always better to soak hay than not to soak!
The amount of hay to be fed should be 1.5% of IDEAL body weight NOT CURRENT weight:
So for a 250kg pony that should ideally weigh 200kg give 3kg of Hay. (200×1.5% = 3)
Always weigh the hay.
This amount of food should be continued until the desired weight is achieved. If NO weight loss has occurred (using your weigh tape not your ‘eye’) this may be reduced to 1% of IDEAL body weight vitamin & mineral supplementation should be provided at the 1% level.
NEVER FEED BELOW 1% as this can cause the insulin resistance to become worse and promote other conditions such as hyperlipaemia, a condition in which high levels of fat are found in the blood and possibly liver due to fat being mobilised by the horse in response to the feed level being below 1% of ideal body weight (in essence starvation).
Exercise is the other crucial component in managing EMS. Once laminitic feet are sound the horse/pony should start on a programme of 2-3 sessions a week of moderate exercise lasting 20-30 minutes. Intensity and duration can be increased over time. Exercise not only aids weight loss but increases insulin sensitivity.
Other feeds/supplements that can be useful for EMS & Laminitis:
Dodson and Horrell – Safe and Sound
Happy Hoof, High Fibre Cubes
High-Fi Lite
Legaphyton
Vitamin A & Biotin @ 20mg/day
Antioxidants – Lysine & Threonine
Arginine
Omega 3 fatty acids.
Magnesium Oxide
Supplements should be use with care and discussion with Paul or Phil at Simply horses should be undertaken before starting to use any of the above products, we are able to provide a wide range of supplements we recommend for animals with EMS and Laminitis. Most of these are in stock and can be collected from us the very next day! You can even re-order online www.simply-horses.net
Confused?
No worries, EMS and Cushing’s Disease share some similarities and are confusing diseases. If you would like to discuss this further or if your horse/pony is showing some of these signs please call us at the practice 0191 3859696 and we can talk about how we investigate these diseases in a relatively simple and non invasive, you may be able to make a real difference to your horse/pony’s life.

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Mudtek equine leg care

We are delighted to announce that here, at Simply Horses, we have been using the new range of cutting-edge wound care products manufactured by local company Fabtek Solutions in Houghton le Spring.
The range includes Meditek Silver wound dressings and the Mudtek range of antibacterial equine leg care products. 

  • Meditek Silver.
    cutting edge wound care technology
    new generation antibacterial carbon and silver wound dressings
    promotes and maintains a healthy wound environment
    are anti-odour, non medicated and non invasive
    designed to enhance wound healing rates
    unique construction means that dressings can be cut to size and shape
  • Mudtek
    The Mudtek range is designed to promote and maintain a healthy environment of the horse’s leg and provide effective protection against the adverse effects of mud and rain.
    designed because prevention is better than cure
    antibacterial horse leg wear – stable boots, pastern wraps or bandage pads/leg wraps
    easy to use and machine washable
    handmade in the UK
    available as bandage pads/leg wraps, pastern wraps and stable boots

What makes these products stand out from the rest is that both ranges use Zorflex branded activated carbon with silver cloth to ensure that the antibacterial qualities are of consistently high quality.  It is a hi-tech carbon fabric with microscopic metallic silver particles. It’s been used in the human wound dressing market for many years and has a really powerful antibacterial action.
This clever material attracts the bacteria, kicking it as it enters the carbon structure while the addition of silver enhances the material’s ability to kill the bacteria.
We are pleased to report that our tests and trials during 2010/11 proved that the products were very effective in helping a variety of mud related conditions and wound types. We would like to say a big thank you to those of you who took part in these trials.
For further information on these fantastic products either speak to Paul or Sarah at Simply Horses or contact www.fabteksolutions.com.

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Equine influenza

WHAT IS EQUINE FLU?

Equine flu is a highly infectious disease that effects the upper and lower respiratory tract and can be found in horses,donkeys and mules.The flu itself is not fatal but could lead on to secondary problems such as bronchitis or pneumonia especially in young/old or horses with underlying problems.If your horse has already had the virus previously he may not redevelop it however this immunisation wont last for life.It can take several weeks to recover from equine flu depending on the strain of the virus.
 
HOW WILL MY HORSE CONTRACT THE FLU VIRUS?

Your horse may catch the virus if they have been in contact with a infected horse or infected waste such as urine/manure. It also can be contracted by inhalation of the virus if its present in the atmosphere or from contact with a human who has been in contact with a infected horse and has not changed clothing and washed sufficiently. 
 
WHAT ARE THE SYMPTOMS?

After contracting the virus your horse will show symptoms within 2-3 days and they will remain infectious for up to 2 weeks,
 
High temperature 103-106f
Dry hacking cough
Discharge from nose which may become thick and discoloured
Loss of appetite
Lack of energy
Stiffness
Swelling in lower limbs
Constipation
Swollen lymph nodes under jaw
Poor performance
 
TREATMENT

Seek advice from your vet immediately
Isolation of horse is very important to minimise spread of disease
Minimise exposure to dust as respiratory tract will be very vulnerable
No exercise(apart from a gentle walk to improve circulation)
Antibiotics if a secondary infection is present
Possible medication to help with breathing
Disinfect where possible
All humans that have been in contact with the virus must thoroughly wash and avoid contact with other horses for 48hours
 
 
 PREVENTION IS BETTER THAN CURE!

There is a vaccination to protect against the virus it consists of a primary course and then followed by booster vaccinations these are extremely important as there is a 100% infectious rate in unvaccinated horses and we are still having confirmed cases of equine flu in the uk. If flu is present horses that are vaccinated may show signs but they will be a lot milder. Competition horses may be required to have more regular vaccinations because of the amount of travelling they do and this may result in a fine if owners don’t comply.
 
 
DON’T DELAY VACCINATE NOW TO STOP THE SPREAD OF EQUINE INFLUENZA

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Revolutionary Mud Fever Treatment From Fabtek At SimplyHorses

Further to our post earlier in the year  http://www.eq9vet.com/mud-fever we spent most of last winter trying out a new form of dressing with a special composition of activated charcoal and very small pieces of crystalline silver called Mudtek and Meditek in some of our severe cases of Mud fever and lymphangitis. These dressings have worked very well and started to be our first line of treatment for such conditions.

For more information go to the main web site at Fabtek Solutions or ring the clinic on 0191 385 9696 for more information or if you have a horse with Mud Fever related issues.

We will be updating this post over the next few months as our experience grows on using this new product.

Paul

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Ragwort

Ragwort

This time of year we need to keep a very close eye on our fields and paddocks for the dreaded Ragwort, some of you may be lucky enough not to be bothered with it but for others it is an ongoing battle with the weed, here is an insight to the weed and how it can affect our animals

What is Ragwort?

Ragwort is a common weed that grows throughout the British Isles, and has always been a problem but recently it has become apparent that the weed may be getting out of control and potentially posing a real threat to the horse population.
Ragwort, also known as Senecio jacobea, contains the toxic compounds pyrrolizidine alkaloids.

Horses are particularly susceptible to ragwort poisoning although other grazing animals are also at risk. Pyrrolizdine alkaloids principally damage the liver, resulting in severe disease and in many cases death.

                                             

Ragwort is normally a biennial – taking two years to fully grow and flower. Seedlings have a spade shaped leaf that is notched at the top. In the first year of growth ragwort has a dense rosette of leaves low to the ground. Ragwort thrives on wasteland, road verges and railway land and from these locations it can spread to pasture. Poor quality and poorly managed horse pastures are particularly susceptible to ragwort infestations. Closely growing grass sward prevents ragwort growth but when the grass becomes thinned out, due to poaching or over grazing, the seeds are able to germinate in the exposed soil. Large plants in their second year grow to between 30 and 100cm high and have woody stems and dark green leaves with ragged, irregular edges. They produce bright yellow, densely packed flowers from May to October. Ragwort can behave like a perennial (flowering every year) if the long stems are cut or mown. Each plant produces thousands of seeds that are dispersed widely by the wind resulting in the rapid spread of the weed. Seeds can also lie dormant for years before germinating

Horses and Ragwort

Most animals will avoid eating ragwort as long as they have an alternative source of good food. This can therefore be a problem on sparse, overgrazed pastures which ragwort can thrive on.
There are anecdotal reports that some horses can develop an acquired taste for the plant, especially if there is little else to eat. When cut or wilted (during hay or haylage making) ragwort loses its bitter taste and becomes more palatable to horses. Drying does not destroy the toxins and dried grass, hay and haylage are common sources of ragwort poisoning.
Ingestion of the pyrrolizidine alkaloid toxin contained in ragwort typically results in the delayed onset of chronic, progressive liver failure.
The liver plays a vital role in the body and is one of the most active organs. The majority of nutrients absorbed from the intestines pass straight to the liver for “processing”. The liver is responsible for regulation of these nutrients to ensure the body has enough protein, carbohydrate and fats. The liver’s other functions include manufacture of many of the proteins essential for life, removal of toxins from the body, aiding the intestinal digestion of food, as an important part of the immune system and storage for several vitamins and trace minerals.

The effects of ragwort toxins are cumulative, thus it is common for ragwort poisoning to occur following consumption
of small quantities of the plant over a long period of time .Development of disease can be delayed from four weeks to six months after eating the plant. Different individuals appear to have different susceptibilities to the toxin.
When a horse eats ragwort the pyrrolizidine alkaloids then pass straight to the liver where they are further metabolised to produce toxic agents that damage liver cells. These damaged liver cells can no longer manufacture protein and cannot multiply in order to replace themselves.
When these cells die they are replaced by fibrous tissue. Slowly, as more and more cells are damaged, the liver shrinks and becomes more fibrous in structure. Eventually there are not enough functional liver cells left to conduct the essential functions of the liver and liver failure is inevitable.

Clinical signs of Ragwort poisoning

The clinical signs (or symptoms) of ragwort poisoning tend to only become apparent when liver failure has occurred. There is often no warning of impending failure. The signs of liver failure are a direct reflection of the loss of liver function. A principle sign is bizarre or depressed behaviour due to altered mental status. This is thought to occur because the liver is no longer able to remove chemicals or toxins from the blood that have harmful effects on
the brain. A second common clinical sign is inflammation of white, unpigmented areas of the skin when they have been exposed to sunlight, known as photosensitization. The degradation of grass in the intestines produces a photodynamic agent (that reacts to sunlight). This agent is normally removed and eliminated by the liver. In hepatic failure this does not occur and concentrations of the agent increase in the body. In areas of unpigmented skin the
activation of the photodynamic agent by sunlight causes damage to and inflammation of the skin. This is not the same as the common problem of sunburn, as suffered by some horses. Other clinical signs of liver failure may also occur, these include jaundice, weight loss and diarrhoea.

Diagnosis and treatment

Diagnosis of liver failure can be aided by blood tests that often show evidence of liver damage and reduced liver function. Performing a liver biopsy can make a definitive diagnosis but is difficult and potentially dangerous. It is hoped that a simple blood test will soon be available to detect early signs of ragwort poisoning before significant, untreatable damage is done to the liver unfortunately in many cases the liver is too damaged for this to occur, although some horses can survive  

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